What is Kisspeptin-10?

Human clinical studiesReproductive research · Last reviewed September 28, 2026

Kisspeptin-10 is the active ten-amino-acid fragment of kisspeptin, a hormone that sits at the top of the reproductive hormone chain.

How does Kisspeptin-10 work?

It activates the KISS1 receptor on GnRH neurons, triggering release of the hormones LH and FSH.

What are researchers studying?

●Puberty and reproductive hormone regulation
●Triggering egg maturation in IVF research
●Hormone-related fertility disorders

Where does the evidence stand?

Human clinical studies

Used in clinical research. Not approved by the FDA.

Quick facts

Research area: Reproductive
Sequence: YNWNSFGLRF-NH2
Also known as: Kisspeptin
Third-party lab results: 1 published COAs →
Tested vendors tracking it: 2 vendors →

Recent peer-reviewed research

The most relevant Kisspeptin-10 studies from the last three years, via PubMed (U.S. National Library of Medicine).

Enzymatic Stability and Comparative Effects of Kisspeptin-14, Kisspeptin-13 and Kisspeptin-10 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation
Metabolites · 2026 Sep 17 · PubMed ↗
Rapid and harmonized analytical workflow for the determination of peptidic and non-peptidic doping agents in dried and liquid blood matrices
The Analyst · 2026 Jul 27 · PubMed ↗
Integrated transcriptomics and miRNA-mRNA network analysis reveals Kisspeptin-10 mediated regulation of EMT and apoptosis in glioblastoma
Computational biology and chemistry · 2026 Apr · PubMed ↗
Kisspeptin-10 Protects Against TNF-α-Induced Chondrocyte Senescence via the SIRT1/p53/p21 Signaling
Journal of biochemical and molecular toxicology · 2025 Jun · PubMed ↗
New Insights in Bovine Follicular Cysts
Reproduction in domestic animals = Zuchthygiene · 2025 Mar · PubMed ↗

Compare Kisspeptin-10

Kisspeptin-10 vs Oxytocin

Related research guides

What is PT-141?What is Oxytocin?

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This guide summarizes published research for educational purposes only. It is not medical advice and does not describe how to use Kisspeptin-10. Citations link to PubMed and are listed for reference — we haven't reviewed or endorsed their findings. Products referenced on The Peptide Audit are sold by third parties for laboratory research use only and are not for human consumption.