What is Kisspeptin-10?

Human clinical studiesReproductive research · Last reviewed September 28, 2026

Kisspeptin-10 is the active ten-amino-acid fragment of kisspeptin, a hormone that sits at the top of the reproductive hormone chain.

How does Kisspeptin-10 work?

It activates the KISS1 receptor on GnRH neurons, triggering release of the hormones LH and FSH.

What are researchers studying?

●Puberty and reproductive hormone regulation
●Triggering egg maturation in IVF research
●Hormone-related fertility disorders

Where does the evidence stand?

Human clinical studies

Used in clinical research. Not approved by the FDA.

Quick facts

Research area: Reproductive
Sequence: YNWNSFGLRF-NH2
Also known as: Kisspeptin
Third-party lab results: 1 published COAs →
Tested vendors tracking it: 2 vendors →

Recent peer-reviewed research

The most relevant Kisspeptin-10 studies from the last three years, via PubMed (U.S. National Library of Medicine).

Investigating the detection of the novel doping‐relevant peptide kisspeptin‐10 in urine using liquid chromatography high‐resolution mass spectrometry
Biomedical chromatography : BMC · 2024 Sep · PubMed ↗
New Insights in Bovine Follicular Cysts
Reproduction in domestic animals = Zuchthygiene · 2025 Mar · PubMed ↗
Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src
Nature communications · 2024 Feb 12 · PubMed ↗
Comprehensive Analysis of Kisspeptin Signaling: Effects on Cellular Dynamics in Cervical Cancer
Biomolecules · 2024 Jul 29 · PubMed ↗
Synthesis and characterisation of DOTA-kisspeptin-10 as a potential gallium-68/lutetium-177 pan-tumour radiopharmaceutical
Journal of neuroendocrinology · 2025 Mar · PubMed ↗

Compare Kisspeptin-10

Kisspeptin-10 vs Oxytocin

Related research guides

What is PT-141?What is Oxytocin?

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This guide summarizes published research for educational purposes only. It is not medical advice and does not describe how to use Kisspeptin-10. Citations link to PubMed and are listed for reference — we haven't reviewed or endorsed their findings. Products referenced on The Peptide Audit are sold by third parties for laboratory research use only and are not for human consumption.