Semax vs Selank
Key differences, research and prices — side by side.
Both are seven-amino-acid peptides developed in Russia and approved there. Semax is derived from ACTH and has been studied for neurotrophic effects such as raising BDNF. Selank is derived from the immune peptide tuftsin and has been studied mainly for anxiety and stress responses.
| Semax | Selank | |
|---|---|---|
| What it is | Semax is a synthetic seven-amino-acid peptide derived from a fragment of ACTH (adrenocorticotropic hormone), developed in Russia. | Selank is a synthetic seven-amino-acid peptide based on tuftsin, a natural immune-system peptide, developed in Russia. |
| How it works | Studies suggest it raises brain-derived neurotrophic factor (BDNF) and influences dopamine and serotonin signaling, without ACTH’s hormonal effects. | Research suggests it affects GABA signaling and the balance of monoamine neurotransmitters, as well as some immune markers. |
| Research areas |
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| Evidence | Human clinical studies | Human clinical studies |
| Regulatory status | Approved as a medicine in Russia. Not approved by the FDA. | Approved as a medicine in Russia. Not approved by the FDA. |
| Research area | Cognitive | Cognitive |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Lowest price | $3.40/mg → | $3.40/mg → |
| Tested vendors | 2 | 2 |
| Third-party lab results | 5 COAs | 5 COAs |
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Educational comparison of published research — not medical advice, and not a recommendation of either compound. Prices are for reference only. Compounds referenced are sold by third parties for laboratory research use only and are not for human consumption.