BPC-157 vs TB-500
Key differences, research and prices — side by side.
BPC-157 is a synthetic 15-amino-acid fragment of a protein from gastric juice, studied mainly in rodent gut and tendon models. TB-500 is a fragment of thymosin beta-4, an actin-binding protein studied for how cells migrate into damaged tissue. Both are supported mostly by animal and lab research.
| BPC-157 | TB-500 | |
|---|---|---|
| What it is | BPC-157 (“body protection compound”) is a synthetic 15-amino-acid peptide based on a fragment of a protein found in human gastric juice. | TB-500 is a synthetic fragment of thymosin beta-4, a 43-amino-acid protein found in almost every human cell. |
| How it works | Laboratory studies suggest it interacts with growth-factor and nitric-oxide signaling involved in blood-vessel formation (angiogenesis) and tissue repair, though its exact receptor target has not been identified. | Thymosin beta-4 binds actin, the protein that forms a cell’s internal scaffold, which influences how cells move and migrate into damaged tissue. |
| Research areas |
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| Evidence | Mostly animal & lab studies | Mostly animal & lab studies |
| Regulatory status | Not approved by the FDA for any use. Human data are limited to a handful of small studies. Prohibited in sport by WADA. | Not approved by the FDA. Most published research uses full-length thymosin beta-4 rather than the TB-500 fragment. Prohibited in sport by WADA. |
| Research area | Tissue Repair | Tissue Repair |
| Sequence | GEPPPGKPADDAGLV | Ac-LKKTETQ |
| Lowest price | $3.96/mg → | $5.10/mg → |
| Tested vendors | 2 | 2 |
| Third-party lab results | 4 COAs | 5 COAs |
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Educational comparison of published research — not medical advice, and not a recommendation of either compound. Prices are for reference only. Compounds referenced are sold by third parties for laboratory research use only and are not for human consumption.