CJC-1295 (no DAC) vs CJC-1295 (with DAC)
Key differences, research and prices — side by side.
The key difference
Both are built on the same GHRH (1-29) sequence. The DAC version carries a “drug affinity complex” that binds albumin in the blood, extending its life from hours to days and producing a sustained rather than pulse-like rise in growth hormone.
| CJC-1295 (no DAC) | CJC-1295 (with DAC) | |
|---|---|---|
| What it is | CJC-1295 without DAC (also called modified GRF 1-29) is a lab-made version of the first 29 amino acids of growth-hormone-releasing hormone (GHRH). | CJC-1295 with DAC is a GHRH analogue attached to a “drug affinity complex” that binds albumin in the blood. |
| How it works | It activates the pituitary’s GHRH receptor, prompting a short pulse of growth-hormone release; its substitutions make it last longer than natural GHRH. | Binding to albumin greatly extends its life in the body, producing a sustained rise in growth hormone and IGF-1 rather than short pulses. |
| Research areas |
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| Evidence | Very limited research | Human clinical studies |
| Regulatory status | Not approved by the FDA. Prohibited in sport by WADA. | Early human studies were published in the mid-2000s; development did not lead to an approved drug. Prohibited in sport by WADA. |
| Research area | GH Secretagogues | GH Secretagogues |
| Sequence | — | — |
| Lowest price | $6.84/mg → | $10.20/mg → |
| Tested vendors | 1 | 1 |
| Third-party lab results | 0 COAs | 2 COAs |
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Educational comparison of published research — not medical advice, and not a recommendation of either compound. Prices are for reference only. Compounds referenced are sold by third parties for laboratory research use only and are not for human consumption.