CJC-1295 (no DAC) vs Ipamorelin
Key differences, research and prices — side by side.
The key difference
They reach growth-hormone release through different receptors. CJC-1295 (no DAC) mimics growth-hormone-releasing hormone at the GHRH receptor; ipamorelin mimics ghrelin at the GHS-R1a receptor. Because the pathways differ, they are often studied together.
| CJC-1295 (no DAC) | Ipamorelin | |
|---|---|---|
| What it is | CJC-1295 without DAC (also called modified GRF 1-29) is a lab-made version of the first 29 amino acids of growth-hormone-releasing hormone (GHRH). | Ipamorelin is a synthetic five-amino-acid peptide from the “growth-hormone secretagogue” family. |
| How it works | It activates the pituitary’s GHRH receptor, prompting a short pulse of growth-hormone release; its substitutions make it last longer than natural GHRH. | It mimics ghrelin at the GHS-R1a receptor to trigger growth-hormone release, and is notable for affecting cortisol and prolactin less than older compounds. |
| Research areas |
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| Evidence | Very limited research | Human clinical studies |
| Regulatory status | Not approved by the FDA. Prohibited in sport by WADA. | Reached human trials but was not approved. Not approved by the FDA. Prohibited in sport by WADA. |
| Research area | GH Secretagogues | GH Secretagogues |
| Sequence | — | Aib-His-D-2Nal-D-Phe-Lys-NH2 |
| Lowest price | $6.84/mg → | $3.96/mg → |
| Tested vendors | 1 | 2 |
| Third-party lab results | 0 COAs | 3 COAs |
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Educational comparison of published research — not medical advice, and not a recommendation of either compound. Prices are for reference only. Compounds referenced are sold by third parties for laboratory research use only and are not for human consumption.