What is Tesamorelin?
Tesamorelin is a stabilized analogue of growth-hormone-releasing hormone (GHRH).
How does Tesamorelin work?
It stimulates the pituitary to release growth hormone, which raises IGF-1 levels.
What are researchers studying?
- ●Abdominal fat in HIV-associated lipodystrophy
- ●Liver fat in clinical studies
- ●Cognition in older adults
Where does the evidence stand?
FDA-approved (Egrifta) since 2010 for reducing excess abdominal fat in adults with HIV-associated lipodystrophy.
Quick facts
- Research area
- GH Secretagogues
- Also known as
- Tesa
- Third-party lab results
- 6 published COAs →
- Tested vendors tracking it
- 2 vendors →
Recent peer-reviewed research
The most relevant Tesamorelin studies from the last three years, via PubMed (U.S. National Library of Medicine).
- Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine PhysiciansThe American journal of sports medicine · 2026 Jan · PubMed ↗
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future DirectionsJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026 Jan 1 · PubMed ↗
- Therapeutic Peptides in Aesthetic, Metabolic and Endocrine Conditions: Effects, Safety, Clinical Applications, and Future PerspectivesInternational journal of molecular sciences · 2026 Apr 27 · PubMed ↗
- The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administrationFrontiers in endocrinology · 2026 · PubMed ↗
- Differing Presentations of Excess Visceral Abdominal Fat in People Living With HIV: Two Clinical Cases Highlighting Distinct Therapeutic Pathways With Tesamorelin and Glucagon-Like Peptide-1 Receptor AgonistsClinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026 May 15 · PubMed ↗
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This guide summarizes published research for educational purposes only. It is not medical advice and does not describe how to use Tesamorelin. Citations link to PubMed and are listed for reference — we haven't reviewed or endorsed their findings. Products referenced on The Peptide Audit are sold by third parties for laboratory research use only and are not for human consumption.